Chemical Chinese name: ethyl iodoacetate
Chemical English name: ethyl iodoacetate; iodoacetic acid ethyl ester
Molecular formula: C4H7IO2
Relative molecular weight: 214.0016 Structural formula:
Recommended and restricted uses of chemicals: as intermediates in organic synthesis.
Emergency Overview: Fatal if swallowed. GHS Hazard Category:
Acute Toxicity - Oral, Category 2
Tag elements:
Pictogram:
Warning: Danger
Hazard Description: Fatal if swallowed. Precautions:
Preventive measures:
Avoid contact with eyes and skin, and wash thoroughly after operation.
No eating, drinking or smoking in the workplace. Incident Response:
Ingestion: Immediately call a Poison Control Center or seek medical attention. Gargle. Safe Storage:
Locked for safekeeping.
Disposal:
This product and its contents and containers are disposed of in accordance with national and local regulations.
Physical and chemical hazards: flammable, its vapors can mix with air to form explosive mixtures.
Health Hazards: The vapor of this product has a strong irritating effect on the eyes, and at 1.4mg/m3, it has a tearjerking effect. Exposure to high concentrations of ethyl ioacetate can cause pulmonary edema and death.
Environmental Hazards: May be harmful to the environment.
√ Substances, mixtures
Component Concentration CAS No.
Ethyl iodoacetate 623-48-3
Inhalation: Quickly leave the scene to a fresh place of air. Keep the airway unobstructed. If breathing difficulties, give oxygen. Breathing and heartbeat stop, cardiopulmonary resuscitation immediately. Seek medical attention.
Skin contact: Remove contaminated clothing immediately and rinse thoroughly with running water. Seek medical attention.
Eye Contact: Immediately separate eyelids and rinse thoroughly with running water or normal saline. Seek medical attention.
Ingestion: Drink an appropriate amount of warm water to induce vomiting (only for awake people). Seek medical attention.
Advice for protecting rescuers: Use personal protective equipment as needed. Special advice for doctors: Symptomatic treatment.
Extinguishing agent: use dry powder, carbon dioxide, and sand to extinguish the fire.
Special Hazard: Combustible in case of open flame and hot topic. Reacts with oxidants. Reacts with water or water vapor to exothermic and produce toxic corrosive gases. Decomposes by heat or comes into contact with acids to release toxic gases. Vapors are heavier than air, diffuse along the ground and easily accumulate in low-lying places. In case of a hot topic, the pressure in the container increases, and there is a risk of cracking and explosion.
Fire fighting precautions and protective measures: Firefighters must wear air breathing apparatus, full body fire and gas protective clothing, and extinguish the fire in the upwind direction. Move the container from the fire to an open area as much as possible. Spray water to keep the fire container cool until the fire is over. If the container in the fire field has changed color or produced sound from the safety pressure relief device, it must be evacuated immediately. Do not use water and foam to extinguish the fire.
Operator protective measures, protective equipment and emergency response procedures: Alert areas are defined according to the area affected by liquid flow and vapor diffusion. Unrelated personnel are evacuated from the crosswind and upwind to the safe area. Eliminate all ignition sources. Emergency responders are advised to wear gas masks, anti-corrosive and anti-gas clothing. Do not come into contact with cracked containers and leaks before wearing appropriate protective clothing. Cut off leaks as much as possible.
Environmental protection measures: prevent leakage into water bodies, sewers, basements, or limited spaces.
Containing and removing methods of leaking chemicals and disposal materials used: Small leaks: Absorb or cover with dry sand or other non-combustible materials and collect in containers. Large leaks: Build a dike or dig a pit for containment. Transfer to a tanker or dedicated collector with a corrosion-resistant pump.
Precautions for operation: Closed operation to provide adequate local exhaust. Prevent steam leakage into the air of the workplace. Operators must be specially trained and strictly follow the operating procedures. It is recommended that operators wear self-priming filter gas masks (full face masks), tape gas suits, and rubber gloves. Keep away from fires and heat sources, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Welding, cutting, etc. cannot be carried out before removing liquids and vapors. Avoid generating fumes. Avoid contact with oxidants, reducing agents, acids, and alkalis. Special attention should be paid to avoid contact with water. Equip with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Harmful substances may remain in emptied containers.
Storage precautions: Store in a cool, dry, well-ventilated warehouse. Keep away from fire and heat sources. Protect from direct sunlight. Keep the container sealed. It should be stored separately from oxidants, reducing agents, acids, alkalis, and edible chemicals, and should not be mixed. Equipped with the corresponding variety and quantity of fire fighting equipment. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials.
Occupational exposure limits:
China: No Standards
United States (ACGIH): No standards
Biological exposure limits: no standard monitoring method has been established:
Determination of toxic substances in the air: desorption of sodium bicarbonate solution - ion chromatography - biological monitoring test method: no standard has been developed
Engineering Controls: Tightly enclosed to provide adequate local exhaust. Personal Protective Equipment:
Respiratory protection: When the concentration in the air exceeds the standard, a filter gas mask (full mask) must be worn. An air respirator should be worn during emergency rescue or evacuation.
Eye protection: Respiratory protection is provided. Skin and body protection: Wear airtight protective clothing.
Hands, Protection: Wear rubber gloves.
| Appearance and characteristics | Colorless oily liquid that gradually decomposes to yellow in light and air |
|---|---|
| pH | No information |
| Melting point (℃) | No information |
| Boiling point (℃) | 179~ 180 |
| Relative density (water = 1) | 1.8080 |
| Relative vapor density (air = 1) | 7.4 |
| Saturated vapor pressure (kPa) | 0.072 (20 ℃) |
| Critical pressure (MPa) | No information |
| Octanol/water partition coefficient | No information |
| Flash point (℃) | 76.67 |
| Spontaneous combustion temperature (℃) | No information |
| Lower explosion limit [% (V/V) ] | No information |
| Upper explosion limit [% (V/V) ] | No information |
| Decomposition temperature (℃) | No information |
| Viscosity (mPa.s) | No information |
| Heat of combustion (kJ/mol) | No information |
| Solubility | Insoluble in water, soluble in ethanol, ether |
| Critical temperature (℃) | No information |
Stability: Stable.
Hazardous reaction: Reacts with strong oxidizing agents, strong reducing agents, acids, alkalis and other prohibited compounds. Reacts with water or water vapor to emit heat and produce toxic corrosive gases. Decomposes by heat or in contact with acids to release toxic gases.
Conditions to avoid: Light, humid air.
Prohibited compounds: strong oxidizing agents, strong reducing agents, acids, bases. Dangerous decomposition products: hydrogen iodide.
Acute toxicity:
LD50:50 mg/kg (rat oral), 50 mg/kg (mouse oral)
Skin irritation or corrosion: No data available.
Eye irritation or corrosion: No data available.
Respiratory or skin allergies: No data available.
Germ cell mutation: No data available.
Carcinogenicity: No data available.
Reproductive toxicity: No data available.
Specific target organ system toxicity - single exposure: no data available.
Specific target organ system toxicity - repeated exposure: no data available.
Hazards from inhalation: No data available.
Ecotoxicity: No data available.
Persistence and degradability:
Biodegradability: No data available.
Non-biodegradable: No data available.
Potential bioaccumulation: No data available.
Migration in soil: No data available.
Waste chemicals: If possible, reuse containers or bury them in designated locations.
Contaminated packaging: return the container to the manufacturer or dispose of it in accordance with national and local regulations. Disposal precautions: refer to relevant national and local regulations before disposal.
United Nations Dangerous Goods Number (UN): 2810
UN Shipping Name: Organic Toxic Liquid, N.O.S. (Ethyl Iodoacetate)
UN Hazard Category: 6.1
Packaging Category: ⅱ
Packaging label:
Marine Pollutants: No
Precautions for transportation: Before transportation, check whether the packaging container is complete and sealed. During transportation, ensure that the container does not leak, collapse, fall or damage. It is strictly forbidden to mix with oxidizing agents, reducing agents, acids, alkalis, and edible chemicals. Transportation vehicles and ships must be thoroughly cleaned and disinfected, otherwise other items shall not be shipped. When shipping, the assembly location should be far away from the bedroom, kitchen, and isolated from the engine room, power supply, fire source, etc. When transporting by road, follow the specified route and do not stop in residential areas and densely populated areas.
The following laws, regulations, rules and standards provide for the management of this chemical:
Law of the People's Republic of China on the Prevention and Control of Occupational Diseases:
Classification and catalogue of occupational diseases: not included
Regulations on the Safety Management of Hazardous Chemicals:
List of Hazardous Chemicals: Included
List of Explosive Hazardous Chemicals: Not Included
List of Hazardous Chemicals under Key Regulation: Not Included
GB 18218-2009 "Identification of Major Hazard Sources of Hazardous Chemicals" (Table 1): Not included.
Regulations on labor protection in workplaces where toxic substances are used:
List of highly toxic substances: not listed
Regulations on the management of precursor chemicals:
Classification and species catalogue of precursor chemicals: not included
International conventions:
Stockholm Convention: not included
Rotterdam Convention: not included
Montreal Protocol: not included
Writing and revising information:
Abbreviations and Acronyms: Training Recommendations:
Reference:
Disclaimer: All relevant information is fully and truthfully provided in this SDS, but we cannot guarantee its absolute breadth and accuracy. This SDS provides safety precautions for this product only to those who have received appropriate professional training and use this product. Individual users who obtain this SDS must make independent judgments about the suitability of this SDS under special conditions of use. In special cases of use, the Chemical Registration Center will not be responsible for any injuries caused by the use of this SDS.
